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Melbourne, Australia (Xinhua/Indonesia Window) – Para ilmuwan di Australia mengidentifikasi sebuah gen kunci yang membantu bakteri usus berbahaya bertahan bahkan terhadap disinfektan standar rumah sakit yang dikhususkan untuk membasmi bakteri tersebut.

Hasil penelitian terbaru mengungkap bahwa bakteri Clostridioides difficile telah memperoleh gen kunci yang membuat spora dormannya kebal terhadap antibiotik dan produk pembersih, menurut pernyataan yang dirilis pada Rabu (30/9) oleh Universitas Monash Australia.

Spora bakteri tersebut dapat tetap dorman dan kemudian aktif di lingkungan yang sesuai, seperti usus manusia, sehingga menimbulkan risiko khusus di rumah sakit, tempat bakteri tersebut dapat menyebabkan diare yang berpotensi mematikan, papar studi yang telah diterbitkan dalam jurnal Nature Communications itu.

Para peneliti menemukan bahwa gen yang resistan terhadap antibiotik tersebut menghasilkan protein yang menggantikan protein kunci pembentuk spora, sehingga bakteri itu dapat menghasilkan spora yang lebih tangguh dan kebal terhadap produk pembersih standar rumah sakit dan suhu pencucian tinggi. Kondisi ini berpotensi menyebabkan infeksi menjadi semakin sulit dikendalikan dan membantu penyebaran galur yang resistan.

Para peneliti kini sedang menyelidiki cara untuk menargetkan spora tersebut dan mengatasi jenis resistansi antibiotik baru ini.

Laporan: Redaksi

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